About This Condition
Don’t let asthma knock the wind out of you. Asthma is a lung disorder characterized by sudden fits of wheezing, coughing, or shortness of breath. According to research or other evidence, the following self-care steps may be helpful.
About This Condition
Asthma is a lung disorder in which spasms and inflammation of the bronchial passages restrict the flow of air in and out of the lungs.
The number of people with asthma and the death rate from this condition have been increasing since the late 1980s. Environmental pollution may be one of the causes of this growing epidemic. Work exposure to flour or cotton dust, animal fur, smoke, and a wide variety of chemicals has been linked to increased risk of asthma.1
Findings from animal and human studies confirm that DTP (diphtheria and tetanus toxoids and pertussis) and tetanus vaccinations can induce allergic responses,2 , 3 , 4 , 5 , 6 and can increase the risk of allergies, including allergic asthma. An analysis of data from nearly 14,000 infants and children revealed that having a history of asthma is twice as great among those who were vaccinated with DTP or tetanus vaccines than among those who were not.7
An asthma attack usually begins with sudden fits of wheezing, coughing, or shortness of breath. However, it may also begin insidiously with slowly increasing manifestations of respiratory distress. A sensation of tightness in the chest is also common.
Healthy Lifestyle Tips
Being overweight increases the risk of asthma.8 Obese people with asthma may improve their lung-function symptoms and overall health status by engaging in a weight-loss program. A controlled study found that weight loss resulted in significant decreases in episodes of shortness of breath, increases in overall breathing capacity, and decreases in the need for medication to control symptoms.9
A set of breathing exercises called Buteyko breathing techniques has been reported to significantly reduce the need for prescription drugs for people with asthma.10 Although the people in this controlled trial experienced an improved quality of life while doing these exercises, objective measures of breathing capacity did not improve, despite the decreased need for drugs.
Antibiotic use during the first year or two of life has been associated with an increased risk of asthma in preliminary studies.11 , 12 Whether this association might result from allergic versus non-allergic effects remains unknown. However, the association does suggest that, until more is known, gratuitous use of antibiotics in early childhood (e.g., to inappropriately treat viral diseases) should be reconsidered. Of course, the appropriate use of antibiotics in the treatment of infections as necessary should not be avoided. Concerns should be discussed with the prescribing physician.
Acupuncture might be useful for some asthmatics. Case reports13 , 14 and preliminary trials15 , 16 , 17 have suggested acupuncture may be helpful for people with asthma, either as a treatment for an acute attack or as a longer term therapy for reducing the number or severity of attacks, decreasing the need for medications, and so on. Placebo-controlled trials using sham (“fake”) acupuncture, however, have been quite contradictory, many of them showing a strong placebo effect that is not significantly improved upon by real acupuncture.18 , 19 , 20 , 21 It is possible that needle insertion in non-acupuncture points has a stimulating effect that benefits asthma. The success of acupuncture may also depend on other factors, such as the type of asthma being treated and certain characteristics of the patient. Nonetheless, since some controlled research has demonstrated positive effects of real acupuncture, people with asthma may want to consider a trial of acupuncture treatment to see if it helps their individual cases.
Chiropractic physicians have reported that manipulation may be helpful for patients with asthma.22 , 23 , 24 In a controlled study, chronic asthmatics received either real or sham chiropractic manipulations for four weeks, after which the treatments were switched for another four weeks. No improvement in measurements of lung function was found at the end of the study. In addition, while both the manipulation and the sham treatment groups reported significant decreases in asthma frequency and severity, there were no differences between the treatments.25 A larger controlled study compared chiropractic manipulation to sham manual treatments in children whose asthma was still a problem despite usual medical management.26 Both groups experienced a significant decrease in symptoms and need for medication, as well as small increases in ability to breathe. These benefits lasted for four months after the treatments were discontinued. Although there was no additional benefit of chiropractic compared to the sham treatments, it is possible that improvements in both groups were real, rather than placebo effects. The sham therapy, which consisted of “soft tissue massage and gentle palpation [touching],” may have had real effects. More research is needed to address this confusing issue.
The right diet is the key to managing many diseases and to improving general quality of life. For this condition, scientific research has found benefit in the following healthy eating tips.
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Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2 Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
1. Blanc PD, Eisner MD, Israel L, Yelin EH. The association between occupation and asthma in general medical practice. Chest 1999;115:1259–64.
2. Mark A, Bjorksten B, Granstrom M. Immunoglobulin E responses to diphtheria and tetanus toxoids after booster with aluminium-adsorbed and fluid DT-vaccines. Vaccine 1995;13:669–73.
3. Mark A, Bjorksten B, Granstrom M. Immunoglobulin E and G antibodies two years after a booster dose of an aluminium-adsorbed or a fluid DT vaccine in relation to atopy. Pediatr Allergy Immunol 1997;8:83–7.
4. Odelram H, Granstrom M, Hedenskog S, et al. Immunoglobulin E and G responses to pertussis toxin after booster immunization in relation to atopy, local reactions and aluminium content of the vaccines. Pediatr Allergy Immunol 1994;5:118–23.
5. Aebischer I, Stadler BM. TH1-TH2 cells in allergic responses: at the limits of a concept. Adv Immunol 1996;61:341–403 [review].
6. Sen DK, Arora S, Gupta S, Sanyal RK. Studies of adrenergic mechanisms in relation to histamine sensitivity in children immunized with Bordetella pertussis vaccine. J Allergy Clin Immunol 1974;54:25–31.
7. Hurwitz EL, Morgenstern H. Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States. J Manipulative Physiol Ther 2000;23:81–90.
8. Camargo CA Jr, Weiss ST, Zhang S, et al. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med 1999;159:2582–8.
9. Stenius-Aarniala B, Poussa T, Kvarnstrom J, et al. Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study. BMJ 2000;320:827–32.
10. Bowler SD, Green A, Mitchell CA. Buteyko breathing techniques in asthma: a blinded randomised controlled trial. Med J Aust 1998;169:575–8.
11. Wickens K, Pearce N, Crane J, Beasley R. Antibiotic use in early childhood and the development of asthma. Clin Exp Allergy 1999;29:766–71.
12. Farooqi IS, Hopkin JM. Early childhood infection and atopic disorder. Thorax 1998;53:927–32.
13. Youguang J. Clinical applications of point Futu. J Tradit Chin Med 1986;6:6–8.
14. Minji W, Yancen Z. Clinical experience of Dr. Shao Jingming in treatment of diseases by puncturing back-shu points. J Tradit Chin Med 1996;16:23–6.
15. Zang J. Immediate antiasthmatic effect of acupuncture in 192 cases of bronchial asthma. J Tradit Chin Med 1990;10:89–93.
16. Sternfeld M, Fink A, Bentwich Z, Eliraz A. The role of acupuncture in asthma: changes in airways dynamics and LTC4 induced LAI. Am J Chin Med 1989;17:129–34.
17. Zwolfer W, Keznickl-Hillebrand W, Spacek A, et al. Beneficial effect of acupuncture on adult patients with asthma bronchiale. Am J Chin Med 1993;2:113–7.
18. Kleijnen J, ter Riet G, Knipschild P. Acupuncture and asthma: a review of controlled trials. Thorax 1991;46:799–802 [review].
19. Jobst KA. Acupuncture in asthma and pulmonary disease: an analysis of efficacy and safety. J Altern Complement Med 1996;2:179–206 [review].
20. Biernacki W, Peake MD. Acupuncture in treatment of stable asthma. Respir Med 1998;92:1143–5.
21. Medici TC. Acupuncture and bronchial asthma. Forsch Komplementarmed 1999;6 Suppl 1:26–8 [in German].
22. Renaud C, Pinchette D. Chiropractic management of bronchial asthma: a literature review. J Chiropractic 1990;27:25–6 [review].
23. Dennis D, Golden D. Manipulative therapy, an alternative treatment for asthma: a literature review. Chiropractic: The Journal of Chiropractic Research, Study and Clinical Investigation 1992;8(2)40–1 [review].
24. Ziegler R, Carpenter D. The chiropractic approach to the treatment of asthma: a literature review. J Chiropractic 1992:29(6):71–3 [review].
25. Nielsen NH, Bronfort, G. Bendix T. et al. Chronic asthma and chiropractic spinal manipulation: a randomized clinical trial. Clin Exp Allergy 1995, 25(1):80–8.
26. Balon J, Aker PD, Crowther ER, et al. A comparison of active and simulated chiropractic manipulation as adjunctive treatment for childhood asthma. N Engl J Med 1998 339(15):1013–20.
27. Forastiere F, Pistelli R, Sestini P, et al. Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children. SIDRIA Collaborative Group, Italy (Italian Studies on Respiratory Disorders in Children and the Environment). Thorax 2000;55:283–8.
28. Lindahl O, Lindwall L, Spangberg A, et al. Vegan regimen with reduced medication in the treatment of bronchial asthma. J Asthma 1985;22:45–55.
29. Javaid A, Cushley MJ, Bone MF. Effect of dietary salt on bronchial reactivity to histamine in asthma. BMJ 1988;297:454.
30. Burney PG, Neild JE, Twort CH, et al. Effect of changing dietary sodium on the airway response to histamine. Thorax 1989;44:36–41.
31. Carey OJ, Locke C, Cookson JB. Effect of alterations of dietary sodium on the severity of asthma in men. Thorax 1993;48:714–8.
32. Medici TC, Schmid AZ, Hacki M, Vetter W. Are asthmatics salt-sensitive? A preliminary controlled study. Chest 1993;104:1138–43.
33. Gotshall RW, Mickleborough TD, Cordain L. Dietary salt restriction improves pulmonary function in exercise-induced asthma. Med Sci Sports Exerc 2000;32:1815–9.
34. Fogarty A, Britton J. The role of diet in the aetiology of asthma. Clin Exp Allergy 2000;30:615–27.
35. Genton C, Frei PC, Pecoud A. Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria. J Asthma 1985;76:40–5.
36. Townes SJ, Mellis CM. Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma. Pediatrics 1984;73:631–7.
37. Chiaramonte LT, Altman D. Food sensitivity in asthma: perception and reality. J Asthma 1991;28:5–9.
38. Rowe AH, Young EJ. Bronchial asthma due to food allergy alone in ninety-five patients. JAMA 1959;169:1158.
39. Sampson HA, Mendelson L, Rosen JP. Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 1992;327:380.
40. Kumar SS, Shanmugasundaram KR. Amrita Bindu—an antioxidant inducer therapy in asthma children. J Ethnopharmacol 2004;90:105–14.
41. Neuman I, Nahum H, Ben-Amotz A. Prevention of exercise-induced asthma by a natural isomer mixture of beta-carotene. Ann Allerg Asthma Immunol 1999;82:549–53.
42. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511–4.
43. REF:Lee DK, Haggart K, Robb FM, Lipworth BJ. Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids. Clin Exp Allergy 2004; 34:110–4.
44. Danesch UC. Petasites hybridus (butterbur root) extract in the treatment of asthma—an open trial. Altern Med Rev 2004;9:54–62.
45. Arm JP, Horton CE, Eiser NM, et al. The effects of dietary supplementation with fish oil on asthmatic responses to antigen. J Allergy Clin Immunol 1988;81:183 [abstract #57].
46. Mickleborough TD, Lindley MR, Ionescu AA, Fly AD. Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma. Chest2006;129:39–49.
47. Broughton KS, Johnson CS, Pace BK, et al. Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production. Am J Clin Nutr 1997;65:1011–7.
48. Dry J, Vincent D. Effect of a fish oil diet on asthma: results of a 1-year double-blind study. Int Arch Allergy Appl Immunol 1991;95:156–7.
49. Thien FC, Woods RK, Waters EH. Oily fish and asthma—a fishy story? Med J Aust 1996;164:135–6 [editorial].
50. Fogarty A, Britton J. The role of diet in the aetiology of asthma. Clin Exp Allergy 2000;30:615–27.
51. Hodge L, Salome CM, Peat JK, et al. Consumption of oily fish and childhood asthma risk. Med J Austral 1996;164:137–40.
52. Nagakura T, Matsuda S, Shichijyo K, et al. Dietary supplementation with fish oil rich in omega-3 polyunsaturated fatty acids in children with bronchial asthma. Eur Respir J 2000;16:861–5.
53. Emelyanov A, Fedoseev G, Krasnoschekova O, et al. Treatment of asthma with lipid extract of New Zealand green-lipped mussel: a randomised clinical trial. Eur Respir J 2002;20:596–600.
54. Palit G, Singh SP, Singh N, et al. An experimental evaluation of antiasthmatic plant drugs from the ancient ayurvedic medicine. Asp Aller Appl Immunol 1983;16:36–41.
55. Singh SP, Sinha KN, Singh N, Kohli RP. Inula racemosa (Puskarmal), Terminalia belerica (Vibhitaki) and Ocimum sanctum (Tulsi) – a preliminary clinical trial in asthma patients. Proc Int Sem Clin Pharmacol Devel Count 1986;1:18–21.
56. Dixit KS, Singh SP, Sinha KN, et al. Inula racemosa (puskarmal), Terminalia belerica (Bibhitaka) and Ocimum sanctum (Tulsi) – a preliminary clinical trial in asthma patients. Proc Int Sem Clin Pharmacol Devel Count 1986;2:22–27.
57. Mansfeld HJ, Höhre H, Repges R, Dethlefsen U. Therapy of bronchial asthma with dried ivy leaf extract. Münch Med Wschr 1998;140:32–6.
58. Neuman I, Nahum H, Ben-Amotz A. Reduction of exercise-induced asthma oxidative stress by lycopene, a natural antioxidant. Allergy 2000;55:1184–9.
59. Haury VG. Blood serum magnesium in bronchial asthma and its treatment by the administration of magnesium sulfate. J Lab Clin Med 1940;26:340–4.
60. Skobeloff EM, Spivey WH, McNamara RM, Greenspon L. Intravenous magnesium sulfate for the treatment of acute asthma in the emergency department. JAMA 1989;262:1210–3.
61. Brunner EH, Delabroise AM, Haddad ZH. Effect of parenteral magnesium on pulmonary function, plasma cAMP, and histamine in bronchial asthma. J Asthma 1985;22:3–11.
62. Rolla G, Bucca C, Caria E, et al. Acute effect of intravenous magnesium sulfate on airway obstruction of asthmatic patients. Ann Allergy 1988;61:388–91.
63. Hill JM, Britton J. Effect of intravenous magnesium sulphate on airway calibre and airway reactivity to histamine in asthmatic subjects. Br J Clin Pharmacol 1996;42:629–31.
64. Bernstein WK, Khastgir T, Khastgir A, et al. Lack of effectiveness of magnesium in chronic stable asthma. A prospective, randomized, double-blind, placebo-controlled, crossover trial in normal subjects and in patients with chronic stable asthma. Arch Intern Med 1995;155:271–6.
65. Rylander R, Dahlberg C, Rubenowitz E. Magnesium supplementation decreases airway responsiveness among hyperreactive subjects. Magnesium-Bulletin 1997;19:4–6.
66. Hill J, Micklewright A, Lewis S, Britton J. Investigation of the effect of short-term change in dietary magnesium intake in asthma. Eur Respir J 1997;10:2225–9.
67. Gontijo-Amaral C, Ribeiro MAGO, Gontijo LSC, et al. Oral magnesium supplementation in asthmatic children: a double-blind randomized placebo-controlled trial. Eur J Clin Nutr 2007;61:54–60.
68. Rajaram D. A preliminary clinical trial of Picrorrhiza kurroa in bronchial asthma. Indian J Pharmacol 1975;7:95–6.
69. Shan BK, Kamat SR, Sheth UK. Preliminary report of use of Picrorrhiza kurroa root in bronchial asthma. J Postgrad Med 1977;23:118–20.
70. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89–95.
71. Lau BH, Riesen SK, Truong KP, et al. Pycnogenol as an adjunct in the management of childhood asthma. J Asthma 2004;41:825–32.
72. Kimura I. Immunologic aspects of kampo medicine. Ann NY Acad Sci 1993;685:529–42.
73. Egashira Y, Nagano H. A multicenter clinical trial of TJ-96 in patients with steroid-dependent bronchial asthma. Ann NY Acad Sci 1993;685:580–3.
74. Nakajima S, Tohda Y, Ohkawa K, et al. Effects of saiboku-to (TJ-96) on bronchial asthma. Ann NY Acad Sci 1993;685:549–60.
75. Bielroy L, Lupoli K. Herbal interventions in asthma and allergy. J Asthma 1999;36:1–65 [review].
76. Stone J, Hinks LJ, Beasley R, et al. Reduced selenium status of patients with asthma. Clin Sci 1989;77:495–500.
77. Flatt A, Pearce N, Thomson CD, et al. Reduced selenium in asthmatic subjects in New Zealand. Thorax 1990;45:95–9.
78. Kadrabova J, Mad’aric A, Kovacikova Z, et al. Selenium status is decreased in patients with intrinsic asthma. Biol Trace Elem Res 1996;52:241–8.
79. Misso NL, Powers KA, Gillon RL, et al. Reduced platelet glutathione peroxidase activity and serum selenium concentration in atopic asthmatic patients. Clin Exp Allergy 1996;26:838–47.
80. Shaw R, Woodman K, Crane J, et al. Risk factors for asthma symptoms in Kawerau children. N Z Med J 1994;107:387–91.
81. Owen S, Pearson D, Suarez-Mendez V, et al. Evidence of free-radical activity in asthma. N Engl J Med 1991;325:586–7 [letter].
82. Hasselmark L, Malmgren R, Zetterstrom O, Unge G. Selenium supplementation in intrinsic asthma. Allergy 1993;48:30–6.
83. Shivpuri DN, Menon MPS, Prakash D. A crossover double-blind study on Tylophora indica in the treatment of asthma and allergic rhinitis. J Allergy 1969;43:145–50.
84. Shivpuri DN, Singhal SC, Parkash D. Treatment of asthma with an alcoholic extract of Tylophora indica: a cross-over, double-blind study. Ann Allergy 1972;30:407–12.
85. Thiruvengadam KV, Haranatii K, Sudarsan S, et al. Tylophora indica in bronchial asthma: a controlled comparison with a standard anti-asthmatic drug. J Indian Med Assoc 1978;71:172–6.
86. Gupta S, George P, Gupta V, et al. Tylophora indica in bronchial asthma—a double blind study. Ind J Med Res 1979;69:981–9.
87. Collipp PJ, Chen SY, Sharma RK, et al. Tryptophane metabolism in bronchial asthma. Ann Allergy 1975;35:153–8.
88. Weir MR, Keniston RC, Enriquez JI, McNamee GA. Depression of vitamin B6 levels due to theophylline. Ann Allergy 1990;65:59–62.
89. Collipp PJ, Goldzier S III, Weiss N, et al. Pyridoxine treatment of childhood bronchial asthma. Ann Allergy 1975;35:93–7.
90. Reynolds RD, Natta CL. Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. Am J Clin Nutr 1985;41:684–8.
91. Sur S, Camara M, Buchmeier A, et al. Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma. Ann Allergy 1993;70:141–52.
92. Zuskin E, Valic F, Bouhuys A. Byssinosis and airway responses due to exposure to textile dust. Lung 1976;154:17–24.
93. Bucca C, Rolla G, Oliva A, Farina J-C. Effect of vitamin C on histamine bronchial responsiveness of patients with allergic rhinitis. Ann Allergy 1990;65:311–4.
94. Schachter EN, Schlesinger A. The attenuation of exercise-induced bronchospasm by ascorbic acid. Ann Allergy 1982;49:146–51.
95. Tecklenburg SL, Mickleborough TD, Fly AD, et al. Ascorbic acid supplementation attenuates exercise-induced bronchoconstriction in patients with asthma. Respir Med 2007;Apr 4:Epub ahead of print.
96. Mohsenin V, Dubois AB, Douglas JS. Effect of ascorbic acid on response to methacholine challenge in asthmatic subjects. Am Rev Respir Dis 1983;127:143–7.
97. Zuskin E, Lewis AJ, Bouhuys A. Inhibition of histamine-induced airway constriction by ascorbic acid. J Allergy Clin Immunol 1973;51:218–26.
98. Ting S, Mansfield LE, Yarbrough J. Effects of ascorbic acid on pulmonary functions in mild asthma. J Asthma 1983;20:39–42.
99. Malo JL, Cartier A, Pineau L, et al. Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma. J Allergy Clin Immunol 1986;78:1153–8.
100. Kordansky DW, Rosenthal RR, Norman PS. The effect of vitamin C on antigen-induced bronchospasm. J Allergy Clin Immunol 1979;63:61–4.
101. Anah CO, Jarike LN, Baig HA. High dose ascorbic acid in Nigerian asthmatics. Trop Geogr Med 1980;32:132–7.
102. Ruskin SL. Sodium ascorbate in the treatment of allergic disturbances. The role of adrenal cortical hormone-sodium-vitamin C. Am J Dig Dis 1947;14:302–6.
103. Urashima M, Segawa T, Okazaki M, et al. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr 2010;91:1255-60.
104. Bray GW. The hypochlorhydria of asthma in childhood. Q J Med 1931;24:181–97.
105. Schafer A, Adelman B. Plasma inhibition of platelet function and of arachidonic acid metabolism. J Clin Invest 1985;75:456–61.
106. Bauer K, Dietersdorfer F, Sertl K, et al. Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma. Clin Pharmacol Ther 1993;43:76–83.
107. Huerta M, Urzua Z, Trujillo X, et al. Forskolin compared with beclomethasone for prevention of asthma attacks: a single-blind clinical trial. J Int Med Res 2010;38:661–8.
108. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: John Wiley & Sons, 1996, 222–4.
109. Guinot P, Brambilla C, Dunchier J, et al. Effect of BN 52063, a specific PAF-ascether antagonist, on bronchial provocation test to allergens in asthmatic patients—a preliminary study. Prostaglandins 1987;34:723–31.
110. Li M, Yang B, Yu H, Zhang H. Clinical observation of the therapeutic effect of ginkgo leaf concentrated oral liquor on bronchial asthma. Chinese J Integrative & Western Med 1997;3:264–7.
111. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: John Wiley & Sons, 1996, 222–4.
112. Felter HW, Lloyd JU. King’s American Dispensatory, 18th ed. Sandy, OR: Eclectic Medical Publications, 1898, 1983, 1199–205.
113. Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy, 11th ed. Sandy, OR: Eclectic Medical Publications, 1919, 1998, 235–42.
114. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:221–2 [trans. Meuss AR].
115. Al-Biltagi M, Isa M, Bediwy AS, et al. L-Carnitine improves the asthma control in children with moderate persistent asthma. J Allergy (Cairo) 2012;2012:509730.
116. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: John Wiley & Sons, 1996, 222–4.
117. Felter HW, Lloyd JU. King’s American Dispensatory, 18th ed. Sandy, OR: Eclectic Medical Publications, 1898, 1983, 1199–205.
118. Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy, 11th ed. Sandy, OR: Eclectic Medical Publications, 1919, 1998, 235–42.
119. Weiss RF. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:221–2 [trans. Meuss AR].
120. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: John Wiley & Sons, 1996, 222–4.
121. Anibarro B, Caballero T, Garcia-Ara C, et al. Asthma with sulfite intolerance in children: A blocking study with cyanocobalamin. J Allergy Clin Immunol 1992;90:103–9.
122. Johnson JL, Wuebbens MM, Mandell R, Shih VE. Molybdenum cofactor deficiency in a patient previously characterized as deficient in sulfite oxidase. Biochem Med Metabol Biol 1988;40:86–93.
123. Sardesai VM. Molybdenum: an essential trace element. Nutr Clin Pract 1993;8:277–81.
124. Moss M. Effects of molybdenum on pain and general health: a pilot study. J Nutr Environ Med 1995;5:55–61.
125. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: John Wiley & Sons, 1996, 222–4.
126. Dorsch W, Ettl M, Hein G, et al. Anti-asthmatic effects of onions: inhibition of platelet-activating factor-induced bronchial construction by onion oils. Int Arch Allergy Appl Immunol 1987;82:535–6.
127. Valdivieso R, Subiza J, Varela-Losada S, et al. Bronchial asthma, rhinoconjunctivitis, and contact dermatitis caused by onion. J Allergy Clin Immunol 1994;94:928–30.
128. Welton AF, Tobias LD, Fiedler-Nagy C, et al. Effect of flavonoids on arachidonic acid metabolism. Prog Clin Biol Res 1986;213:231–42.
129. Cazzola P, Mazzanti P, Bossi G. In vivo modulating effect of a calf thymus acid lysate on human T lymphocyte subsets and CD4+/CD8+ ratio in the course of different diseases. Curr Ther Res 1987;42:1011–7.
130. Kouttab NM, Prada M, Cazzola P. Thymomodulin: Biological properties and clinical applications. Med Oncol Tumor Pharmacother 1989;6:5–9 [review].
131. Genova R, Guerra A. A thymus extract (thymomodulin) in the prevention of childhood asthma. Pediatr Med Chir 1983;5:395–402.
132. Bagnato A, Brovedani P, Comina P, et al. Long-term treatment with thymomodulin reduces airway hyperresponsiveness to methacholine. Ann Allergy 1989;62:425–8.
133. Anibarro B, Caballero T, Garcia-Ara C, et al. Asthma with sulfite intolerance in children: A blocking study with cyanocobalamin. J Allergy Clin Immunol 1992;90:103–9.
134. Johnson JL, Wuebbens MM, Mandell R, Shih VE. Molybdenum cofactor deficiency in a patient previously characterized as deficient in sulfite oxidase. Biochem Med Metabol Biol 1988;40:86–93.
135. Sardesai VM. Molybdenum: an essential trace element. Nutr Clin Pract 1993;8:277–81.
136. Moss M. Effects of molybdenum on pain and general health: a pilot study. J Nutr Environ Med 1995;5:55–61.
137. Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci 1993;90:7915-22.
138. Grievink L, Zijlstra AG, Ke X, Brunekreef B. Double-blind intervention trial on modulation of ozone effects on pulmonary function by antioxidant supplements. Am J Epidemiol 1999;149:306-14.
139. Trenga CA, Koenig JQ, Williams PV. Dietary antioxidants and ozone-induced bronchial hyperresponsiveness in adults with asthma. Arch Environ Health 2001;56:242-9.
140. Romieu I, Sienra-Monge JJ, Ramirez-Aguilar M, Tellez-Rojo MM, Moreno-Macias H, Reyes-Ruiz NI, et al. Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants. Am J Respir Crit Care Med 2002;166:703-9.
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