Drug Information
Hydralazine is a drug used to lower blood pressure in people with
hypertension
. Hydralazine relaxes the muscles that control the diameter of blood vessels. This relaxation allows the blood vessels to dilate (open wider), lowering blood pressure.
Common brand names:
Apresoline
Summary of Interactions with Vitamins, Herbs, & Foods
Types of interactions:
Beneficial
Adverse
Check
Replenish Depleted Nutrients
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Vitamin B6
Vitamin B6 can bind to hydralazine to form a complex that is excreted in the urine, increasing vitamin B6 loss.1 This may lead to vitamin B6 deficiency.2 People taking hydralazine should consult with their doctor to discuss the possibility of vitamin B6 supplementation.
Potential Negative Interaction
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.
References
1. Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 131–2.
2. Raskin NH, Rishman RA. Pyridoxine-deficiency neuropathy due to hydralazine. N Engl J Med 1965;273:1182–5.
